Synthesis, F-18-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

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作者： Loeser, Reik ^[1] ; Bader, Miriam ^[1] ; Kuchar, Manuela ^[1] ; Wodtke, Robert ^[1] ; Lenk, Jens ^[1] ; Wodtke, Johanna ^[1] ; Kuhne, Konstantin ^[1] ; Bergmann, Ralf ^[1] ; Haase-Kohn, Cathleen ^[2] ; Urbanova, Marie ^[1] ; Steinbach, Joerg ^[1] ; Pietzsch, Jens ^[1]

作者单位： Helmholtz Zentrum Dresden Rossendorf, Inst Radiopharmaceut Canc Res, Bautzner Landstr 400, D-01328 Dresden, Germany ^[1] Univ Chem & Technol, Dept Phys & Measurements, Prague 16628, Czech Republic ^[2]

关键词 Radiolabelled peptides F-18-fluorobenzoylation Difficult peptide sequences Claudin family of tight junction proteins Molecular imaging Small animal positron emission tomography

发布时间 2019-10-09

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