A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus-论文-万方医学网

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A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus

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第一作者： Zoutman, Willem H.

作者： Zoutman, Willem H. ^[1] ; Nell, Rogier J. ^[2] ; Versluis, Mieke ^[3] ; Pico, Ingrid ^[4] ; Vu, T. H. Khanh ^[5] ; Verdijk, Robert M. ; van der Burg, Mirjam ; Langerak, Anton W. ; van der Velden, Pieter A.

作者单位： Dept Dermatol,Leiden Univ ^[1] Dept Ophthalmol,Leiden Univ ^[2] Dept Pediat,Leiden Univ ^[3] Dept Pathol,Erasmus MC ^[4] Dept Immunol,Erasmus MC ^[5]

关键词 B cell Switched B cell Quantification Digital PCR VDJ rearrangements Class switch recombination Allelic involvement TUMOR-INFILTRATING LYMPHOCYTES IMMUNOGLOBULIN QUANTIFICATION VALIDATION EXPRESSION GUIDELINES EXCLUSION CIRCLES DESIGN ASSAYS

发布时间 2022-07-29

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A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus

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A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus

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