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Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

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作者单位: Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany [1] Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States [2] MRC Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's [3] Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Netherlands [4] Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA, United States [5] Singapore Eye Research Institute, National University of Singapore, Singapore, Centre for Eye [6] Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital [7] NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London EC1V 2PD [8] Croatian Centre for Global Health, University of Split Medical School, Split, Croatia [9] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, National Eye Institute [10] National Human Genome Research Institute, National Eye Institute, National Institutes of Health [11] Dept of Ophthalmology, Hospital 'Sestre Milosrdnice', Zagreb, Croatia [12] Department of Ophthalmology and Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands [13] Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of [14] Institute of Human Genetics, Technische Universit?t München, Munich, Germany, Institute of Human [15] Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and [16] Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute [17] Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands, Department of Internal [18] Princess Alexandra Eye Pavilion, Edinburgh, United Kingdom [19] School of Medicine and Public Health, University of Newcastle, Newcastle, Australia, Hunter Medical [20] Medical Systems Biology, Department of Pathology and Department of Microbiology and Immunology, The [21] Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom [22] Institute of Epidemiology I, Neuherberg, Germany [23] Institute of Human Genetics, Technische Universit?t München, Munich, Germany [24] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada [25] Institute of Population Genetics, National Research Council of Italy, Sassari, Italy [26] Dipartimento di Scienze Chirurgiche, Clinica Oculistica Universita' degli studi di Cagliari [27] Centre for Molecular Epidemiology, National University of Singapore, Singapore, Singapore [28] Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands [29] Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA [30] MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, United Kingdom [31] Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University [32]
发布时间 2013-11-20
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