Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity-论文-万方医学网

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Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity

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第一作者： Le Nouen, Cyril

作者： Le Nouen, Cyril ^[1] ; Luongo, Cindy L. ^[1] ; Yang, Lijuan ^[1] ; Mueller, Steffen ^[2] ; Wimmer, Eckard ^[1] ; DiNapoli, Joshua M. ^[1] ; Collins, Peter L. ^[3] ; Buchholz, Ursula J. ^[1]

作者单位： NIAID, Infect Dis Lab, NIH, Bethesda, MD 20892 USA ^[1] Codagenix Inc, Stony Brook, NY USA ^[2] SUNY Stony Brook, Dept Mol Genet & Microbiol, Stony Brook, NY 11794 USA ^[3]

关键词 codon pair optimization genome recoding negative-strand RNA virus respiratory syncytial virus

发布时间 2020-10-14

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Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity

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Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity

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