Brain Pyroglutamate Amyloid-beta is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic

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作者： Hook, Gregory ^[1] ; Yu, Jin ^[2] ; Toneff, Thomas ^[3] ; Kindy, Mark ; Hook, Vivian

作者单位： Amer Life Sci Pharmaceut, La Jolla, CA USA ^[1] Med Univ S Carolina, Dept Neurosci, Charleston, SC 29425 USA ^[2] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, Dept Neurosci, La Jolla, CA 92093 USA ^[3]

关键词 Pyroglutamate amyloid-beta cathepsin B BACE1 A beta PP protease transgenic AD mice inhibitor cysteine protease secretion

发布时间 2015-10-14

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Journal of Alzheimer's disease

2014年41卷1期

129-149页

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Brain Pyroglutamate Amyloid-beta is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic

Journal of Alzheimer's disease

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Journal of Alzheimer's disease

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Brain Pyroglutamate Amyloid-beta is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic

Journal of Alzheimer's disease

相似文献

Journal of Alzheimer's disease

相关期刊

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