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Effects of Endurance and Endurance-strength Exercise on Renal Function in Abdominally Obese Women with Renal Hyperfiltration:A Prospective Randomized Trial

摘要ObjectiveObesity is associated with kidney defects.Physical activity is a key element in the treatment of obesity.The aim of this study was to compare the effect of endurance and endurance-strength training on kidney function in abdominally obese women. MethodsForty-four abdominally obese women were randomized to endurance training or endurance-strength training, three times a week for 3 months. Before and after the intervention, kidney function was assessed by measuring blood creatinine, urine creatinine, and urine albumin levels, and the albumin-to-creatinine ratio and glomerular filtration rate (GFR) were calculated. ResultsRenal hyperperfusion was present in both groups before the study. Following both types of physical activity, similar modifications of the investigated parameters were observed, but with no significant between-group differences.Both courses of training led to a significant increase in blood creatinine and a subsequent decrease in the GFR. A significant increase in urine creatinine and album levels, though not exceeding the range for microalbuminuria, was not accompanied by any difference in the albumin-to-creatinine ratio after endurance-strength training alone. ConclusionThree months of either endurance or endurance-strength training has a favorable and comparable effect on renal function in abdominally obese women with renal hyperfiltration.

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作者单位 Department of Education and 0besity Treatment and Metabolic Disorders, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland [1] Department of Internal Medicine, Metabolic Disorders and Hypertension, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland [2] Department of Physiology, Biochemistry and Hygiene, Poznań University School of Physical Education, ul. Królowej Jadwigi 27/39, 61-871 Poznań, Poland [3] Department of Physiology, Poznań University of Medical Sciences, ul. ?wi?cickiego 6, 60-781 Poznań, Poland [4] Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, ul. Szpitalna 27/33, 60-572 Poznań, Poland [5] Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers University, New Jersey Medical School, International Center for Public Health, 225 Warren Street, Room E230P Newark, New Jersey 07103-3535, USA [6]
DOI 10.3967/bes2016.095
发布时间 2016-12-08(万方平台首次上网日期,不代表论文的发表时间)
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