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Air Pollution and Cardiac Biomarkers in Heart Failure:A Scoping Review

摘要Ambient air pollution is increasingly being recognized as a risk factor for heart failure;however,its effects on cardiac biomarkers remain unclear.This scoping review assessed the existing evidence on the association between air pollution and cardiac biomarkers in heart failure,described the key concepts,synthesized data,and identified research gaps.Following the PRISMA-ScR guidelines,PubMed,Embase,Web of Science,and CNKI databases were searched for studies on air pollution,heart failure,and biomarkers.A total of 765 records were screened,and 81 full texts were assessed for eligibility,resulting in 15 studies.The results showed that the exposure to particulate matter was associated with elevated N-terminal pro-B-type natriuretic peptide and troponin levels.Several studies have linked particulate matter exposure to a higher cardiovascular risk and heart failure biomarkers.Inflammatory and oxidative stress markers were consistently elevated across studies,supporting the biological relevance of these associations.However,few studies have focused specifically on populations with heart failure or clinically relevant biomarkers,and the evidence for gaseous pollutants remains inconclusive.These findings highlight the need to integrate environmental risk assessment into heart failure care and inform policy efforts to reduce the pollution-related cardiovascular burden.Further research should address these gaps through improved exposure assessments and the integration of mechanistic evidence.

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DOI 10.3967/bes2025.120
发布时间 2025-12-17(万方平台首次上网日期,不代表论文的发表时间)
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生物医学与环境科学(英文版)

生物医学与环境科学(英文版)

2025年38卷11期

1430-1443页

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