摘要外周T细胞淋巴瘤(PTCL)是一种高度侵袭性的包含多种亚型的淋巴瘤。PTCL在现有治疗方案下预后较差,其治疗仍是一个挑战。在2016年第58届美国血液学会(ASH)年会中,多项研究报道了PTCL治疗的最新进展。 brentuximab vedotin联合CHP方案、罗米地辛联合普拉曲沙等方案为PTCL患者提供了更多的选择,PI3K抑制剂等新型药物的发现也逐步进入临床试验,给PTCL患者带来了福音。
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abstractsPeripheral T-cell lymphoma (PTCL) is a kind of highly aggressive lymphoma which contains a collection of subgroups. The patients with PTCL have poor prognosis under current chemotherapy regimens, so the treatment of PTCL remains a big challenge. Brentuximab vedotin combined with CHP regimen, pralatrexate in combination with romidepsin and other regimens have set up more options for patients with PTCL. Novel agents, such as PI3K inhibitors, which entered into clinical trials, bring good news to PTCL patients.
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