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Potential efficacy and mechanism of medicinal plants on chronic kidney disease-associated vascular calcification:a review

摘要Vascular calcification is a crucial risk factor that affects the incidence and mortality of cardiovascular disease in chronic kidney disease patients.Modern medicine relies on calcium-phosphorus binding agents,calcium mimetics,active vitamin D,and hemodialysis to prevent and treat vascular calcification,however,their efficacy is unsatisfactory and adverse reactions often occur.Medical plant therapy can act as an integrative regulator in patients with chronic kidney disease-associated vascular calcification,which can significantly improve patients'symptoms,but its specific mechanism has not been fully elucidated yet.In this paper,we reviewed the domestic and international theoretical studies on the pathogenesis mechanism of chronic kidney disease-associated vascular calcification in recent years,summarized eight active ingredients of medicinal plants as well as four compound formulas for improving chronic kidney disease-associated vascular calcification,and explored the mechanism of action of herbal medicine,which will provide a new strategy for promoting the prevention and treatment of vascular calcification.

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作者 Han-Qing Zhang [1] Shuang Wu [1] Xin Chen [1] Ya-Xuan Fang [1] Qiu-Mei Lan [1] Zi-Jun Zhou [1] Yan-Heng Qiao [1] Jie Li [1] Yan-Ru Zhao [1] Ming Pei [1] Bo Yang [1] 学术成果认领
作者单位 Department of Nephropathy,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China [1]
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DOI 10.53388/TMR20231123002
发布时间 2024-11-22(万方平台首次上网日期,不代表论文的发表时间)
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