换一批Proteomic analysis of mTOR inhibition-mediated phosphorylation changes in ribosomal proteins and eukaryotic translation initiation factors
摘要Dear Editor,The mammalian target of rapamycin (mTOR),as a critical energy sensor and cell-growth regulator,controls protein synthesis,autophagy and many important cellular processes through forming functional distinct complexes,mTORC1 and mTORC2.mTORC1 that is sensitive to rapamycin,regulates cell growth and protein synthesis,while mTORC2 that is insensitive to rapamycin,regulates cellular metabolism and the cytoskeletal organization (Gingras et al.,2001;Hay and Sonenberg,2004).
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栏目名称
DOI
10.1007/s13238-016-0279-0
发布时间
2016-09-28（万方平台首次上网日期，不代表论文的发表时间）
基金项目
This work was supported in part by the National Natural Science Foundation of China （(Grant No.31270871 to H.T.D) and MOEC 2012Z02293 (H.T.D)）
:the National Basic Research Program (973 Program)
(No.2014CBA02005 to H.T.D.):
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