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CT增强在肺癌非手术治疗疗效评价中的作用

Assessing no-surgical treatment response in bronchogenic carcinoma with contrast material-enhanced computed tomography

摘要Objective: The aim of the study was to evaluate the efficacy of contrast material-enhanced computed tomography(CT) in assessing no-surgical treatment response in bronchogenic carcinoma. Methods: The 67 patients with bronchogeniccarcinoma after no-surgical treatment underwent two-phase contrast material-enhanced computed tomography. Two spiralCT scans were obtained at 25 and 90 s respectively after nonionic contrast material was administrated via the antecubital veinat a rate of 4 mL/s by using an autoinjector. Precontrast and postcontrast attenuation values on every scan were recordedand peak height was calculated. Enhancement pattern was evaluated on the image obtained at 25 and 90 s after injection ofcontrast medium. Results: Precontrast attenuation value, postcontrast attenuation values at 25 and 90 s were (41.26 ± 7.77)Hu, (56.45 ± 10.48) Hu, (70.82 ± 11.99) Hu, respectively. No statistically significant difference in precontrast attenuation wasfound between our results in this study and the results in our old study (mean precontrast attenuation 40.70 Hu) which wastreatment [(29.40 ± 10.73) Hu] were significantly lower than that of bronchogenic carcinoma without any therapy obtained inour old study (mean peak height 35.79 Hu) (t = -4.874, P = 0.001 < 0.05). The 39 among 67 cases appeared homogeneousenhancement at 90 s. At 25 s, there were 26 cases with inhomogeneous enhancement, 9 cases with homogeneous enhancement,2 cases with central enhancement, and 2 cases with peripheral enhancement among the 39 cases. Conclusion: Peakheights can reflect the blood supply of bronchogenic carcinoma and might be an index for evaluation of no-surgical treatmentresponse in bronchogenic carcinoma.

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分类号 R73
栏目名称 Original Articles
DOI 10.1007/s10330-010-0044-4
发布时间 2010-06-12
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中德临床肿瘤学杂志(英文版)

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