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The indigenous populations as the model by nature to understand human genomic-phenomics interactions

摘要The advancement of genomic technology has progressed in a lightning speed. However, the understanding of genotype-phenotype interactions has come to a bottleneck owing to the complex interplays between the human biology and environment, hence posing hindrance to materialising precision medicine in a holistic manner. The newly emerging discipline on human phenomics may be the solution. We argue that the indigenous populations serve as an ideal model to excavate our understanding on genomic-environmental-phenomics interactions. This review provides an overview on the potential advantages of investigating the human phenomics in the indigenous populations, and the challenges ahead.

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作者 Boon-Peng Hoh [1] Thuhairah Abdul Rahman [2] 学术成果认领
作者单位 Faculty of Medicine and Health Sciences, UCSI University, Kuala Lumpur 56000, Malaysia [1] Clinical Pathology Diagnostic Centre Research Laboratory, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh 47000, Malaysia [2]
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DOI 10.15302/J-QB-021-0251
发布时间 2024-07-26(万方平台首次上网日期,不代表论文的发表时间)
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