换一批摘要In humans, infection with the coronavirus, especially the severe acute respiratory syndrome coronavirus (SARS-CoV) and the emerging Middle East respiratory syn-drome coronavirus (MERS-CoV), induces acute respiratory failure, resulting in high mortality. Irregular coronavirus related epidemics indicate that the evolutionary ori-gins of these two pathogens need to be identified urgently and there are still ques-tions related to suitable laboratory animal models. Thus, in this review we aim to highlight key discoveries concerning the animal origin of the virus and summarize and compare current animal models.
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关键词
animal modelscoronavirusesreservoirsthe Middle East respiratory syndrome (canonical form)the severe acute respiratory syndrome
栏目名称
DOI
10.1002/ame2.12017
发布时间
2018-08-23（万方平台首次上网日期，不代表论文的发表时间）
基金项目
This review was supported by the National Key Research and Development Project of China（(2016YFD0500304)）
CAMS Innovation Fund for Medical Sciences（(CIFMS, 2016-I2M-1-014\2016-12M-006)）
the Chinese National Major S & T Project（(2017ZX10304402-001-003)）
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