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A novel small-animal locomotor activity recording device for biological clock research

摘要The rodent running-wheel recording apparatus is a reliable approach for studying cir-cadian rhythm.This study demonstrated how to construct a simple and intelligent running-wheel recording system.The running wheel was attached to the cage's base,whereas the Hall sensor was attached to the cage's cover.Then,the RJ25 adaptor relayed the running signal to the main control board.Finally,the main control board was connected to the USB port of the computer with the USB connection.Data were collected using the online-accessible,self-created software Magturning.Through Magturning,generated data were saved and exported in real time.Afterward,the device was validated by collecting data on the locomotor activities of mice under dif-ferent light conditions.In conclusion,this new device can record circadian activity of rodents.Our device is appropriate for interdisciplinary investigations related to biological clock research.

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作者 Yi-Long Wu [1] Ming Zhong [2] Jun Yin [3] Wei-Jie Ou [4] Yu-Bin Zhuang [5] Nan-Wen Zhang [6] Su Lin [7] Yue-Yong Zhu [7] 学术成果认领
作者单位 Endoscopy Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China [1] Department of Endocrinology,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China [2] Chuangke Workshop Technology Co.,Ltd,Shenzhen,China [3] Department of Digestive Nutrition,Fujian Children's Hospital,Fuzhou,China [4] Experimental Animal Center,Fujian Medical University,Fuzhou,China [5] Department of Pharmacology,Fujian Medical University,Fuzhou,China [6] Department of Hepatology,Hepatology Research Institute,Clinical Research Center for Liver and Intestinal Diseases of Fujian Province,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China [7]
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DOI 10.1002/ame2.12381
发布时间 2024-04-07(万方平台首次上网日期,不代表论文的发表时间)
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动物模型与实验医学(英文)

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