摘要This study was conducted to investigate the effects of dietary supplementation with yeast culture(YC)and organic selenium(Se)during late gestation and lactation on reproductive performance,milk quality,piglet preweaning performance,antioxidant capacity,and secretion of immunoglobulin in multiparous sows.A total of 160 healthy cross-bred sows(Landrace x Yorkshire,mean parity 4.1 ± 0.3)were randomly assigned to 4 groups as follows:1)high nutrient(HN),3,420 kcal/kg digestible energy(DE)and 18.0％crude protein(CP);2)low nutrient(LN),3,240 kcal/kg DE and 16.0％CP;3)LN+YC,LN diet+10 g/kg YC;4)LN+YC+Se,LN diet+10 g/kg YC+organic Se(1 mg/kg Se).Feeding trials of sows started from d 85 of pregnancy to d 35 of lactation.Compared with sows in the LN group,sows fed the LN+YC+Se diet had greater litter weaning weight,average litter gain,and milk fat content(14-d and 25-d milk)(P ＜ 0.05).The content of malonaldehyde(MDA)(colostrum and 14-d milk)was lesser,and the activity of glutathione peroxidase(GSH-Px)(colostrum and 25-d milk)was greater when sows were fed the LN+YC+Se diet,compared with sows fed the LN diet(P ＜ 0.05).Supplementation of YC and organic Se in the nutrient-restricted diet improved sows'reproductive performance and pig weaning body weight by enhancing the antioxidant capacity and fat content in milk.