摘要Recent discoveries have underscored the cross-talk between intestinal microbes and their hosts.Notably,intestinal microbiota impacts the development,physiological function and social behavior of hosts.This influence usually revolves around the microbiota-gut-brain axis (MGBA).In tbis review,we firstly outline the impacts of the host on colonization of intestinal microorganisms,and then highlight the influence of intestinal microbiota on hosts focusing on short-chain fatty acid (SCFA) and tryptophan metabolite-mediated MGBA.We also discuss the intervention of intestinal microbial metabolism by dietary sup-plements,which may provide new strategies for improving the welfare and production of pigs.Overall,we summarize a state-of-the-art theory that gut microbiome affects brain functions via metabolites from dietary macronutrients.