摘要篇首: Megavoltage radiation therapy (RT) is the primary treatment modality for nasopharyngeal carcinoma (NPC). Treatment results have been steadily improving with rapid technological advances and better knowledge on optimization of dose fractionation. During the past decade, RT techniques have evolved from conventional 2-dimensional (2D) to 3-dimensional (3D) complex technique with multiple conformal fields and intensity-modulation. There is little controversy that intensity-modulated technique (IMRT) is recommended if resources permit, dosimetric studies show clear improvement in dose distribution, with conformity of high dose to concave tumor targets and sharp dose gradient for adequate tumor coverage and better protection of adjacent normal tissues.
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