摘要Teacher-student relationships play a vital role in improving college students' academic performance and the quality of higher education.However,empirical studies with substantial data-driven insights remain limited.To address this gap,this study collected 3278 questionnaires from seven universities across four provinces in China to analyze the key factors affecting college students' academic performance.A machine learning framework,CQFOA-KELM,was developed by enhancing the Fruit Fly Optimization Algorithm(FOA)with Covariance Matrix Adaptation Evolution Strategy(CMAES)and Quadratic Approximation(QA).CQFOA significantly improved population diversity and was validated on the IEEE CEC2017 benchmark functions.The CQFOA-KELM model achieved an accuracy of 98.15％and a sensitivity of 98.53％in predicting college students' academic performance.Additionally,it effectively identified the key factors influencing academic performance through the feature selection process.