摘要Objective::To explore the separation condition for 90Sr using crown ether resin, in order to establish a fast method for analysis of 90Sr in food and environmental samples. Methods::Stable strontium isotope ( 88Sr) was used to simulate the radioactive 90Sr, and the concentration of 88Sr in elution solution was detected using inductively coupled plasma mass spectrometry (ICP-MS). The separation conditions were investigated through batch experiment. Results::Under the optimized experimental conditions, the maximum adsorption capacity of crown ether resin was 22.28 mg/g. 4.0-8.0 mol/L nitric acid made it easier for the Sr 2+ to load on the resin, and 20 mL ultrapure water was used to rinse the chromatographic column to achieve a good separation effect, by which the recoveries of Sr 2+ were nearly close to 100%. The average recovery rates of 4 samples were 60.25%, 69.26%, 75.09% and 66.33%, respectively. Conclusions::Crown ether resin has very good selectivity and adsorption for 90Sr. The optimized conditions were high-efficiency and easy to operate. The separation method has great potential for the fast analysis of 90Sr in food and environmental samples.