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Comparison of dose sparing between visual feedback guided- and active breathing coordinator-assisted- deep inspiration breath hold for left whole breast radiotherapy

Comparison of dose sparing between visual feedback guided- and active breathing coordinator-assisted- deep inspiration breath hold for left whole breast radiotherapy

摘要Objective::To compare the benefits of dosimetry between different deep inspiration breath hold (DIBH) techniques.Methods::A total of sixty patients eligible for adjuvant left whole-breast radiotherapy were enrolled, with equal allocation ( n = 30 per group) to either vDIBH or active breathing coordinator (ABC)-DIBH techniques. All patients received computed tomography (CT) scans in both free breathing (FB)and DIBH states. The target and crucial organs at risks (OARs) were precisely delineated on both breathing states of CT scans. The primary endpoints focused on assessing the irradiation exposure to OARs, including the heart, left anterior descending coronary (LAD) artery, left lung and stomach. Results::The dose sparing advantage was more pronounced with vDIBH compared to ABC-DIBH, correlating with its enhanced lung expansion capacity. The relative dose reduction of heart's mean dose (32 % ± 18 % vs. 22 % ± 15 %, P = 0.018) and LAD artery's mean dose (43 % ± 25 % vs. 30 % ± 16 %, P = 0.023) were improved with vDIBH comparing with ABC-DIBH. However, regardless of whether vDIBH or ABC-DIBH was employed, our study did not demonstrate the protective effect of DIBH on the left lung. Conclusion::The vDIBH group demonstrated a remarkable dose reduction for OARs mentioned above compared to the ABC-DIBH group, attributed to greater lung inflation during vDIBH.

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作者 Quan Rencui [1] Yang Dong [2] Chen Hongtao [2] Li Xianming [2] Li Zihuang [2] Liu Jingwen [2] Zhang Yucong [2] Liu Jianfeng [2] 学术成果认领
作者单位 Jinan University, 510632 Guangzhou, China [1] Department of Radiation Oncology, Shenzhen People's Hospital, Second Clinical Medical College, Jinan University, First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518000, China [2]
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DOI 10.1016/j.radmp.2026.01.004
发布时间 2026-02-28(万方平台首次上网日期,不代表论文的发表时间)
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放射医学与防护(英文)

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