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Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity

摘要Recent studies have shown that global translational reprogramming is an early activation event in patterntriggered immunity,when plants recognize microbe-associated molecular patterns.However,it is not fully known whether translational regulation also occurs in subsequent immune responses,such as effectortriggered immunity (ETI).In this study,we performed genome-wide ribosome profiling in Arabidopsis upon RPS2-mediated ETI activation and discovered that specific groups of genes were translationally regulated,mostly in coordination with transcription.These genes encode enzymes in.volved in aromatic amino acid,phenylpropanoid,camalexin,and sphingolipid metabolism.The functional significance of these components in ETI was confirmed by genetic and biochemical analyses..Our findings provide new insights into diverse translational regulation of plant immune responses and demonstrate that translational,coordination of metabolic gene expression is an important strategy for ETI.

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作者单位 Howard Hughes Medical Institute, Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA;Department of Plant Biology, Ecology, and Evolution, Oklahoma State University, Stillwater, OK 74078, USA [1] Howard Hughes Medical Institute, Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA [2] National Key Laboratory of Crop Genetic Improvement, National Centre of Plant Gene Research(Wuhan), Huazhong Agricultural University, 430070 Wuhan, China [3] Howard Hughes Medical Institute, Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA;National Key Laboratory of Hybrid Rice, Institute for Advanced Studies(IAS), Wuhan University, Wuhan, Hubei 430072, China [4] Howard Hughes Medical Institute, Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA;Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Sciences, Shandong University,Qingdao, China [5] Howard Hughes Medical Institute, Department of Biology, Duke University, Box 90338, Durham, NC 27708, USA;David H.Murdock Research Institute, Kannapolis, NC 28081, USA [6]
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发布时间 2020-04-24
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分子植物(英文版)

分子植物(英文版)

2020年13卷1期

88-98页

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