Intraarterial and intravenous contrast enhanced CT and MR imaging of multi-step hepatocarcinogenesis defining the early stage of hepatocellular carcinoma development

摘要Liver cancer is the second leading cause of cancer deaths in men worldwide, and the 6th and 7th cause of cancer deaths in men and women in developed countries. 70％-90％ of primary liver cancer is hepatocellular carcinoma. Hepatitis B or C viruses and chronic inflammation due to alcohol intake are the main risk factors for hepatocellular carcinoma. One of the key approaches for the early detection of hepatocellular carcinoma is to understand the specific imaging findings of liver nodules in the multi-step hepatocrcinogenesis process. In this article, we review the imaging findings of multistep hepatocarcinogenesis, with a focus on the early detection of malignant, cirrhotic nodules with CT and MRI.

作者 Satoshi Kobayashi ^[1] Kazuto Kozaka ^[2] Toshifumi Gabata ^[2] Osamu Matsui ^[2] Tetsuya Minami ^[3] 学术成果认领

作者单位 Department of Quantum Medical Technology, Kanazawa University Graduate School of Medical Sciences, Kanazawa 920-0942, Japan;Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Kanazawa 920-8641, Japan ^[1] Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Kanazawa 920-8641, Japan ^[2] Department of Radiology, Kanazawa Medical University, Uchinada 920-0293, Japan ^[3]

关键词 Hepatocellular carcinoma multistep hepatocarcinogenesis early hepatocellular carcinoma dysplastic nodule CT MRI

栏目名称 Review

DOI 10.20517/2394-5079.2020.24

发布时间 2020-09-28

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