摘要BACKGROUND:?Liver? surgery? has? gone? through? the? phases?of? wedge? liver? resection,? regular? resection? of? hepatic? lobes,?irregular? and? local? resection,? extracorporeal? hepatectomy,?hemi-extracorporeal? hepatectomy? and? Da? Vinci? surgical?system-assisted? hepatectomy.? Taking? advantage? of? modern?technologies,? liver? surgery? is? stepping? into? an? age? of? precise?liver?resection.?This?review?aimed?to?analyze?the?comprehensive?application?of?modern?technologies?in?precise?liver?resection. <br> DATA? SOURCE:?PubMed? search? was? carried? out? for? English-language?articles?relevant?to?precise?liver?resection,?liver?anatomy,?hepatic? blood? inflow? blockage,? parenchyma? transection,? and?down-staging?treatment. <br> RESULTS:?The?3D?image?system?can?imitate?the?liver?operation?procedures,? conduct? risk? assessment,? help? to? identify? the?operation? feasibility? and? confirm? the? operation? scheme.? In?addition,?some?techniques?including?puncture?and?injection?of?methylene?blue?into?the?target?Glisson?sheath?help?to?precisely?determine?the?resection.?Alternative?methods?such?as?Pringle?maneuver? are? helpful? for? hepatic? blood? inflow? blockage? in?precise?liver?resection.?Moreover,?the?use?of?exquisite?equipment?for? liver? parenchyma? transection,? such? as? cavitron? ultrasonic?surgical?aspirator,?ultrasonic?scalpel,?Ligasure?and?Tissue?Link?is?also?helpful?to?reduce?hemorrhage?in?liver?resection,?or?even?operate?exsanguinous?liver?resection?without?blocking?hepatic?blood? flow.? Furthermore,? various? down-staging? therapies?including?transcatheter?arterial?chemoembolization?and?radio-frequency? ablation? were? appropriate? for? unresectable? cancer,?which?reverse?the?advanced?tumor?back?to?early?phase?by?local?or?systemic?treatment?so?that?hepatectomy?or?liver?transplantation?is?possible. <br> CONCLUSIONS:?Modern? technologies? mentioned? in? this?paper?are?the?key?tool?for?achieving?precise?liver?resection?and?can? effectively? lead? to? maximum? preservation? of? anatomical?structural? integrity? and? functions? of? the? remnant? liver.? In?addition,? large? randomized? trials? are? needed? to? evaluate? the?usefulness?of?these?technologies?in?patients?with?hepatocellular?carcinoma?who?have?undergone?precise?liver?resection.