摘要Pancreatic cancer has an overall dismal prognosis compared to most other malignancies.In general,only about 15％-20％of pa-tients are deemed upfront resectable at time of diagnosis,with a similar proportion presenting with either borderline or locally advanced disease[1].Novel and more effective treatment reg-imens including FOLFIRINOX have made yet more patients be-come resectable,with up to 60％reported in some centers[2].Technical advances in surgery continue to literally explore new anatomical territory[3].More aggressive attitude towards resec-tion of involved vessels has provided opportunity for curative at-tempt resections,even for a subpopulation of biological respon-ders staged with pre-treatment unresectable disease[4,5].How-ever,while surgery is the dominant modality for a potential cu-rative approach to pancreatic cancer,there is a subgroup of pa-tients scheduled for surgery who ends up with an aborted resec-tion during explorative laparotomy,also referred to as an"open-close laparotomy".The reasons for such non-resection events are manyfold and have likely changed over time.Indeed,in one Ital-ian study the non-resection rate remained constant at about 25％over two decades[6].While many institutional series report non-resection rates in the same range,these figures may be influenced by patient selection,referral patterns and institutional policies to-wards resection and surgical aggressiveness[2,4,6].