摘要IntroductionLiver cancer remains a global health challenge,and its in-cidence is increasing worldwide.It is estimated that by 2025,more than one million individuals will be affected by liver cancer annually[1,2].In recent years,ablation has become a widely ac-cepted treatment option for patients with primary and secondary liver malignancies[3].The commonly used ablation method for liver cancer is thermal ablation,including radiofrequency ablation,microwave ablation,laser ablation and cryoablation.However,many tumors cannot be treated with thermal ablation owing to hazardous tumor location.Thermal ablation of tumors adjacent to large blood vessels is associated with a higher incidence of incom-plete eradication(heat-sink effect).In addition,these modalities can cause thermal injury to important structures such as bile ducts or intestines in the vicinity of the ablated area and can therefore be contraindicated[4,5].