换一批摘要Severe acute pancreatitis(SAP)is a serious systemic disease as-sociated with strong local inflammatory reactions and serious sys-temic pathophysiological disorders caused by trypsin spillover.Pa-tients with SAP are prone to exhibit gastrointestinal dysfunction.Meanwhile,gastrointestinal dysfunction further aggravates the sys-temic inflammatory response and metabolic abnormalities,result-ing in a more critical condition of SAP.Gastrointestinal dysfunction is considered to be the"trigger"of multiple organ dysfunction syn-drome[1].Thus,it is important to maintain gastrointestinal home-ostasis in the treatment of SAP.
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