换一批摘要Hepatitis E virus(HEV)is the primary cause of acute viral hep-atitis globally and is prevalent in many developing countries.Sero-logical epidemiology studies[1,2]suggest that approximately one-third of the global population has been infected with HEV.There are an estimated 20 million new cases of HEV infection worldwide annually.World Health Organization(WHO)reported that HEV caused approximately 44 000 deaths in 2015,which accounted for 3.3％of deaths from viral hepatitis[3,4].Clinically,most cases of acute hepatitis E have a self-limiting course.However,co-infection with other viruses can increase the risk of acute or subacute liver failure.
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