换一批摘要Scavenger receptor class B type Ⅰ (SR-BI) is a high-affinity receptor for high-density lipoprotein (HDL). The primary role of this receptor is the selective uptake of HDLs in the liver through reverse cholesterol transport. SR-BI interacts with HDL to regulate lipid metabolism and affect various vascular cell functions involved in atherosclerosis (As). In addition, SR-BI is involved in the development of malignant tumors and infectious diseases. This article reviews the function and potential therapeutic targets of SR-BI in As, malignancies, and infectious diseases.
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DOI
10.1515/ii-2017-0163
发布时间
2018-01-30（万方平台首次上网日期，不代表论文的发表时间）
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