摘要INTRODUCTIONAnti-resorptive treatment (ART) with agents such as bispho-sphonate (BPs) or denosumab (Dmab) is commonly practiced in patients with osteoporosis and bone metastatic diseases.1 In patients undergoing a long-term ART, a rare intraoral lesion called medication-related osteonecrosis of the jaw (MRONJ) may develop, which is clinically defined as exposed bone through intraoral and/or extraoral fistula that persists for more than 8 weeks without a history of radiation therapy.
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