广州市多动倾向儿童全血中六种微量元素分析
Analysis of six trace elements in blood in hyperactivity children in Guangzhou city
摘要目的 了解广州市有多动倾向儿童全血中微量元素含量水平,探讨儿童全血微量元素水平与多动性的关系.方法 随机选取在我院就诊的有多动倾向的478名2~13岁儿童,按年龄段分为4组Gl组,幼儿期(1~3岁)35例,G2组,学龄前期(4~6岁)180例,学龄期分为两组,G3组,为7~10岁228例,G4组,为>10岁35例.用原子吸收法测定全血Cu、Zn、Ca、Mg、Fe、Pb等6种微量元素含量,并用SPSS 13.0统计软件包对全血微量元素进行统计分析.结果 Zn元素和Ca元素在不同年龄组中差异有统计学意义(P<0.05),而其它元素Cu、Mg、Fe、Pb在不同年龄组中差异不显著.有多动倾向儿童的锌缺乏率很高,具体缺乏率G1组为40.0%,G2组为59.4%,G3组65.4%,G4组54.3%,钙缺乏率占第二位,具体钙缺乏率G1组成20.2%,G2组38.3%,G3组41.7%,G4组71.4%.各年龄组铅超标达22%以上,I组铅过量占到绝大部分.结论 锌元素的缺乏很可能是有多动倾向或多多动症的一个重要因素,缺钙和低水平铅暴露也可能是促进有多动倾向的因素.
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abstractsObjective To investigate the contents of the trace elements in the whole blood of hyperactivity children in Guangzhou, and the relationship between the trace elements and hyperactivity. Methods Randomly selected 478 children being hospitalized in our hospital who have the hyperactivity of the 2-year-old children to 13, and divided into 4 groups by ages, G1 group, 35 cases infant(1 to 3 years),G2 group, pre-school period 180 cases (4 to 6 years), School-age were divided into two groups, G3 group, 228 cases (7 to 10 years), G4 group, 35 cases (≥ 10 years).Levels of Ca, Zn, Fe, Cu、Mg and Pb were measured by BH7100 and BH2100 atomic absorption spectrometer from 478 cases of children blood Levels of trace elements analyzed by SPSS 13.0 statistical package. Results Among the different ages, the content of Zn and Ca was different(P<0.05),but the contents of Cu, Mg, Fe, Pb was no different (P>0.05).The deficiency rate of Zn is very high among hyperactivity children. The deficiency rate of Zn is G1 40.0%, G2 59.4%, G3 65.4%, G4 54.3%. The deficiency rate of Ca ranked second. The exceeding rate of Pb is above 22% in different groups. Conclusions The deficiency of Zn might be an important factor for child hyperactivity, and the deficiency of Calcium and lower lead exposure may be another factors.
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