摘要目的 通过对婴幼儿不同接种部位的接种后反应情况观察,为婴幼儿选择安全理想的预防接种部位提供依据.方法 2010年5-6月期间将我院岗贝预防接种门诊1032名接种B型流感嗜血杆菌疫苗的2岁以下婴幼儿随机分为3组,接种部位分别采用股外侧肌、三角肌及臀肌.观察3组儿童接种后不良反应的发生情况.结果 股外侧肌、三角肌及臀肌肌肉注射30min内局部反应率分别为2.1%(7例)、1.1%(4例)、1.5%(5例);30分钟至72 h内局部反应率分别为9.6%(32例)、8.7%(32例)及10.9%(36例);发热率分别为4.2%(14例)、3.3%(12例)及2.7%(9例).3组局部反应发生率和发热反应发生率的差异均无统计学意义(x2=1.34,1.96,P＞0.05).结论 选用臀肌、三角肌及股外侧肌肌肉注射法接种疫苗都是安全的,但2岁以下婴幼儿的理想接种部位还是股外侧肌中部肌肉.

abstractsObjective To secure the ideal choice of infant vaccination site. Method May 2010 to June Pui Kong hospital during the vaccination clinic 1032 Haemophilus influenzae type B vaccination vaccine in infants under 2 years of age were randomly divided into 3 groups were inoculated with vastus lateralis site, triangular and gluteal muscles. 3 groups were observed after vaccination of chíldren the inci dence of adverse reactions. Results The vastus lateralis, deltoid and gluteal intramuscular injection of 30min, the local reaction rate was 2.1% ( 7 cases ), 1.1% ( 4 cases ), 1.5% ( 5 cases ); 30 minutes to 72h response rate within the local 9.6% ( 32 cases ), 8.7% ( 32 cases ) and 10.9% ( 36 cases ); Heating rates were 4.2% ( 14 cases ), 3.3% ( 12 cases ) and 2.7% ( 9 cases ). 3 groups of local reaction rates and the incidence of fever was no significant difference( x2=1.34, 1.96, P＞ 0.05 ). Conclusion The use gluteal, deltoid and vastus lateralis intramuscular vaccination method is safe, but infants and young children under the age of 2, the ideal injection site is the central muscle vastus lateralis muscle.