摘要成年女性痤疮（adult female acne，AFA）是指25岁以上女性的痤疮，包括持续型和迟发型，其病因、临床特征及进展与青春期前痤疮有所不同。临床常见面部下半部分的炎性皮损，易出现炎症后色沉及瘢痕，且皮肤比青少年痤疮更加敏感，对局部用药耐受性更差。它具有基因易感性，部分患者有高雄血症或高胰岛素血症，痤疮丙酸杆菌耐药菌株与慢性病程有关。治疗方案多选择联合治疗，需考虑大量因素，复发频繁，维持治疗必不可少。本文综述了成年女性痤疮的临床表现、发病机制及治疗。

abstractsAdult female acne (AFA) is defined as one that affects women over the age of 25 years old. It includes presistent acne and late acne. The causes, clinical characteristics, and evolution of adult female acne are different to these of adolescent acne. It is characterized by inflammatory lesions mainly on the lower part of the face. Post-inflammatory hyperpigmentation is common and the scars can occur. The skin of adult female may be more sensitive than that of adolescents, with less tolerance to topical medications. Genetic predisposition has been considered an important predisposing factor. Some patients have hyper-androgenism or hyperinsulinemia. Drug-resistant strains of propionibacterium acne are associated with its chronicity. It should be treated combinedly. In choosing the treatment methods, numerous factors must be taken into account. Frequent relapses make maintenance treatment essential. Clinical characteristics, pathogenesis, and treatment of adult female acne are summarized in this paper.