摘要目的:分析行腹腔镜手术治疗的子宫内膜异位症（EMS）Ⅲ、Ⅳ期患者联合注射亮丙瑞林治疗对卵巢功能及临床症状的影响。方法:选取2018年1月至2019年1月本院收治的EMS Ⅲ、Ⅳ期患者64例，随机分为常规组和研究组，各32例。常规组采用腹腔镜手术治疗，研究组联合皮下注射亮丙瑞林治疗。比较两组治疗总有效率、卵巢功能及排卵率。结果:研究组治疗后FSH、LH和E2水平显著低于常规组（均 P＜0.01），排卵率显著高于常规组（75.0%比43.75%），且卵巢体积明显缩小[（3.8±0.3）cm 3比（7.6±0.7）cm 3]，差异具有统计学意义（ P＜0.01）。常规组显效12例，有效10例，研究组分别为20例及10例，研究组有效率更高（ P＜0.01）。 结论:EMS Ⅲ、Ⅳ期患者采取腹腔镜手术联合亮丙瑞林治疗有助于卵巢修复，改善临床症状，提高治疗有效率。

abstractsObjective:To analyze the effects of injection of lepredrin on ovarian function and clinical symptoms in patients with endometriosis (EMS) stage Ⅲ and Ⅳ treated by laparoscopic surgery.Methods:64 stage Ⅲ and Ⅳ EMS patients admitted to our hospital from January, 2018 to January, 2019 were randomly divided into a conventional group and a study group, with 32 cases in each group. Both groups were treated by laparoscopic surgery; in addition, the study group took lepredrin. The total response rates, ovarian function, and ovulation rates of the two groups were compared.Results:After the treatment, the levels of FSH, LH, and E2 in the study group were significantly lower than those in the conventional group (all P＜0.01).The ovulation rate was significantly higher and the ovarian volume was significantly lower in the study group than in the conventional group [75.0% vs. 43.75% and (3.8±0.3) cm 3 vs. (7.6±0.7) cm 3; both P＜0.01]. In the conventional group, 12 cases were markedly effective, and 10 cases were effective;and in the study group, 20 and 10 cases; the effective rate of the study group was higher ( P＜0.01). Conclusion:Forstage Ⅲ and Ⅳ EMS patients, laparoscopic surgery combined with lepredrin is helpful for ovarian repair and improvement of clinical symptoms and treatment efficacy.