摘要Hepatic arterial infusion chemotherapy(HAIC)is widely used in the clinical treatment of patients with advanced liver cancer.Because of the need for re-puncture and catheterization for each postoperative perfusion chemo-therapy and long-term bed rest with a catheter for pump infusion of chemotherapeutic drugs in patients undergo-ing HAIC,the risk of venous thromboembolism(VTE)is significantly increased.This article reviews the inci-dence characteristics,risk factors,prevention strategies,and research progress of HAIC-related VTE in patients.The incidence of VTE in HAIC patients is as high as 5%-20%.The main risk factors for HAIC-related VTE in-clude tumor-related hypercoagulable state,catheter indwelling,and vascular endothelial damage caused by che-motherapeutic drugs.Preventive measures for HAIC-related VTE include mechanical prevention,drug preven-tion,and comprehensive management strategies.This review provides a reference for preventing VTE in patients with liver cancer undergoing perfusion chemotherapy.More high-quality studies are needed to optimize VTE pre-vention strategies for patients undergoing HAIC.