摘要目的 探讨在CT引导下125I粒子植入微创治疗非小细胞肺癌(NSCLC)辐射防护护理干预的措施及注意事项.方法 对89例NSCLC患者实施有计划和验证的125I粒子植入治疗,进行围手术期的全程防护护理干预,观察分析植入治疗的成功率、疗效参数和并发症发生率.结果 科学合理的辐射防护护理干预能保障放射性粒子植入的剂量学分布符合有效和微创的原则,植入治疗成功率达到100%,局部控制有效率为96.7%,1年生存率为92.2%;早期和晚期放射反应发生率分别为14.6%和1.1%.未出现放射性泄漏污染事件.结论 包含全程放疗计划和验证的125I粒子植入疗法,结合科学的辐射防护护理干预措施,对提高NSCLC的疗效和明显降低并发症的发生具有重要的临床价值.

abstractsObjective To research radiation protective nursing intervene and important notice of ~(125)I seeds minimally invasive implantation in non-small cell lung carcinoma(NSCLC)by CT.Methods Under the system of therapy planning system(TPS)and posologic validation,~(125)I seeds were implanted in 89 cases of NSCLC patients.The consistent radiation protective nursing intervene was used in perioperative period management.The operative successful rate,therapeutic effect and complication rate was observed.Results The scientific radiation protective nursing intervene can ensure that the radioactive dose distribution of ~(125)I seed implantation brachytherapy is consistent with the principles of effective and minimally invasive.The operative successful rate was 100%.The local control rate and 1 year survival rate respectively was 97.4%and 92.2%.But the early and later incidence rate of radioactive damaging effect was 14.6% and 1.1%respectively.Leakage of radioactive contamination has not occurred.Conclusion The consistent TPS and posologic validation ~(125)I seeds implantation integrated scientific radiation protective nursing intervene.It is very important to improve the therapeutic effect of NSCLC and reduce the incidence of complications.