摘要目的 了解特种部件接触人员老年期心脏结构及心功能情况,探讨辐射可能对心血管系统的影响及程度.方法 应用西门子G60彩色多普勒仪对50例男性老年期(＞60岁)特种部件接触人员(接触组)与50名军分区干休所未接触特种部件的老干部(＞60岁)(对照组)进行心脏瓣膜组织结构指标、心室收缩及舒张功能敏感指标检查,同时进行常规心电图检查,并进行对比分析研究.结果 与对照组比较,接触组射血分数、短轴缩小率的差异无统计学意义(t=1.52,t=1.68,P均＞0.05),心输出量、每搏排血量、每搏指数、心室舒张早期E峰速度/舒张晚期A峰速度(E/A)值均显著降低(t=11.81、t=7.11、t=7.34和t=7.88,P均＜0.001),左房、左室扩大(t=4.85,P＜0.01;t=6.61,P＜0.001).心电图显示,接触组窦性心率不齐和心肌供血不足显著高于对照组(x2=9.72和x2=5.19,P均＜0.05).结论 长期小剂量慢性辐射对心血管系统可能有一定的影响,因此动态监测心脏结构及功能的变化有利于保护特种部件接触人员的安全与健康.

abstractsObjective To investigate the structural and functional changes of heart in elderly soldiers who was working with radiation producing equipments. The involvement of cardiovascular system in radiation and its intensity was investigated in this study. Methods Fifty elderly males (＞60 years old) who were exposed to radiation producing equipments (exposure group) and 50 elderly (＞60 years old) retired male commanders without radiation exposure history (control group) were enrolled in this study. Echocardiographic evaluation of cardiac structure and function was conducted with Siemens Sonline Gt0 ultrasound system. 12-lead electrocardiogram ( ECG ) and routine physical examination had also been done in both groups. Results Ejection fraction, minor axis reduced rate had no distinct difference between exposure group and control group (t=1.52 and t=1.68, P＞0.05). Cardiac output, cardiac stroke volume, stroke index, ventricular diastolic flow velocity E/A ratios in exposure group were lower than control group ( t= 11.81, t=7.11, t=7.34 and t=7.88, P＜0.001); left atrial and ventricular expansion is larger in exposure group ( t=4.85, P＜0.01; t=6.61, P＜0.001 ); also, higher rates of ECG abnormalities was found in exposure group (x2=9.72 and x2=5.19, P＜0.05 ). Conclusion Chronic low dose radiation may have effects on the cardiovascular system, so dynamic monitoring of changes in cardiac structure and function is worth on the safety and health for persons who may exposure to radiation and help to prevent early and long-term effects of radiation.