摘要多模式显像已成为临床应用的发展趋势。目前，PET-CT是最经典且成熟的多模式显像方法，已广泛应用于临床。MRI是临床上另一种常见的显像方法，它没有辐射性，不仅能提供精细的解剖信息和更好的软组织对比度，还能通过磁共振波谱分析等分子显像技术提供多种功能信息。联合PET和MRI仪的PET-MRI多模式显像设备将可能对科研与临床应用产生更深远的影响。该文主要综述PET-MRI的研制进展、现状及存在的挑战，并展望其应用前景。

abstractsMultimodality imaging is the general trend of clinical imaging.PET-CT is one of the most classic and mature multimodality imaging methods and is widely used today.MRI is another kind of conventional imaging method, in contrast to CT, MRI can not only yield images with higher soft-tissue contrast and better spatial resolution but also provide some functional information by special imaging techniques such as MRS.The combination of PET and MRI for simultaneous data acquisition should have far-reaching consequences for clinical and scientific study.This review describes the progress to date and talks about the problems met in the development of PET-MRI and look forward to its potential application.