摘要炎症是机体对抗侵入性病原体和其他损伤的第一道防线,它在组织修复和消除有害病原体方面起着重要作用,但过度炎症反应或炎症消退的延迟将破坏组织中的正常细胞.因此,寻求一种理想的炎症显像方法一直都是临床和科研工作者所追求的目标.白细胞核素显像探针通过即时示踪白细胞,高特异性地反映炎症的病理过程,能早期准确反映炎症程度和预后评价.笔者就此类炎症显像剂的临床应用和研究进行综述.

abstractsInflammation plays a significant role in the defense against invasive pathogens and injuries.This process helps in tissue repair and elimination of harmful pathogens.However,over or extended inflammatory reaction is harmful to normal cells.Numerous clinical and scientific studies have explored an ideal inflammatory imaging method.Radionuclide imaging can reveal the degree and pathological process of inflammation and prognosticate therapeutic response using instant and highly specific monitoring of leukocyte activation and distribution.This study was performed to provide a brief description of the clinical application and progress in the development of radionuclide probes.