摘要目的 通过探讨慢性失眠患者失眠严重程度、抑郁情绪与生活质量的相关性,评估影响患者生活质量的主要因素.方法 连续收集126例成年慢性失眠患者,根据失眠严重程度指数量表(ISI)得分分为亚临床、中度、重度失眠三组,根据贝克抑郁问卷(BDI)得分分为伴和不伴抑郁两组,用SF-36健康调查量表(SF-36)评分,分别对生活质量进行比较.结果 失眠程度重的患者SF-36(除机体疼痛外)得分低(P<0.01);伴有抑郁情绪的患者SF-36(除机体疼痛外)得分低(P<0.05);相关性分析得出ISI得分与SF-36(除机体疼痛外)得分呈负相关(P<0.05),BDI得分与SF-36得分呈显著负相关(P<0.01);控制BDI变量偏相关分析,ISI得分与SF-36(生理功能、生理职能、总体健康、活力和生理健康)得分呈负相关(P<0.05);控制ISI变量偏相关分析,BDI得分与SF-36得分(除生理机能和机体疼痛外)呈显著负相关(P<0.01).结论 慢性失眠患者失眠严重程度与生活质量相关,但与慢性失眠相关的抑郁情绪起到主要作用,这提示慢性失眠治疗中应注重改善患者情绪问题.

abstractsObjective To assess the main influencing factors of patients' life quality through explore the correlation among insomnia severity,depression symptom and quality of life (QOL) in patients with chronic insomnia.Methods A total of 126 patients diagnosed with chronic insomnia were included.The patinets were divided into sub-clinical group,moderate insomnia group and serious insomnia group according to the score of Insomnia Severity Index (ISI).The Beck Depression Inventory (BDI)was used to evaluate the depression symptom and the Medical Outcomes Study Short Form-36 (SF-36) was used to evaluate the quality of life.Results Patients with severe insomnia and depression symptom had lower SF-36(except the body pain) scores.The ISI scores had negative correlation with SF-36 scores(except the body pain)(P<0.05).The BDI scores had negative correlation with SF-36 scores(P<0.01).After controlled for BDI scores, ISI scores had negative correlation with SF-36 scores in RF, RP,GH, VT and physical well-being (P<0.05).After controlled for ISI scores, BDI scores had negative correlation with SF-36 scores in RP, GH, VT, SF, RE, MH and mental and physical well-being (P<0.01).Conclusion Depression symptom and insomnia severity have significantly negative affect on QOL and depression symptom has more negative impacts on QOL of patients with chronic insomnia.