换一批
换一批摘要慢性阻塞性肺疾病和心血管疾病均是多发病,经济负担和社会负担严重,二者存在一定的相关性.慢性阻塞性肺疾病患者中心血管疾病的发病率、病死率增加,这一相关性可能与全身炎症反应、血管功能障碍、氧化应激、缺氧等因素有关.本文将对二者相关性及其可能的机制方面的研究进展进行综述.
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abstractsChronic obstructive pulmonary disease (COPD) and cardiovascular disease are two common and frequent diseases, which have serious economic and social burden. There is a correlation between COPD and cardiovascular disease. The morbidity and mortality of cardiovascular disease are increased in patients with COPD. This correlation may be explained by systemic inflammation, vascular dysfunction,oxidative stress,hypoxia,etc. This review is focused on the relationship between COPD and cardiovascular disease and it's potential mechanisms.
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关键词
慢性阻塞性肺疾病心血管疾病全身炎症氧化应激血管功能障碍缺氧Chronic obstructive pulmonary diseaseCardiovascular diseaseSystemic inflammationVascular dysfunctionOxidative stressHypoxia
主题词
肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive)心血管疾病(Cardiovascular Diseases)炎症(Inflammation)血管(Blood Vessels)低氧(Hypoxia)
分类号
R5
DOI
10.3760/cma.j.issn.1673-436X.2011.01.009
发布时间
2011-03-03
基金项目
中华医学会临床医学慢性呼吸道疾病科研专项资金
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