摘要慢性阻塞性肺疾病(COPD)是以慢性气道炎症及渐进的肺实质的毁坏为特征,大部分情况是由于吸烟引起的[1],居当前世界上死亡原因的第四位,主要是通过摧毁终末支气管及肺泡壁来增加通气量.患者通常死于肺气肿的对症治疗(包括:氧疗、抗感染、止咳化痰、解痉平喘、舒张支气管等)的无效及逐渐出现的呼吸衰竭[2].人们在不断地寻找治疗COPD的方法,除早期干预及对症支持处理外,肺移植成为主要的根治方法.但随着科学技术的不断发展,干细胞疗法受到了广大研究者的关注,其中脐带血间充质干细胞( UCB- MSCs)治疗COPD尤为瞩目.本文就此项研究的相关进展综述如下.

abstractsChronic obstructive pulmonary disease (COPD) which in the current world fourth to the cause of death,is a chronic airway inflammation and gradual destruction of lung parenchyma as feature,most of the situation is due to smoking causes[1],mainly by destroying terminal bronchial and alveolar walls,to increase ventilation.Patients usually died of emphysema semeiologically treats (including:oxygen cure,anti-infection,reduce phlegm,smooth wheezing,diastolic spasm of bronchial etc) invalid and gradually appear of respiratory failure [2].People are constantly looking for treatment method of COPD,in addition to early intervention and semeiologically support in the disposal,lung transplant to become a major radical method.But along with the development of science and technology,stem cell therapy by the mass of the attention,the umbilical cord blood mesenchymal stem cells (MSCs) treatment of COPD UCB-particularly outstanding.This article reviewed the relevant research progress are as follows.