换一批
换一批非小细胞肺癌靶向治疗的一个新趋势:EML4-ALK融合基因
A new trend of targeted therapy in non-small cell lung cancer: EML4-ALK fusion gene
摘要在非小细胞肺癌个体化治疗成为共识的今天,靶向治疗是其中的重要组成部分,EML4-ALK是近期发现的非小细胞肺癌的新的分子亚型.在亚洲、女性、无或轻度吸烟、肺腺癌患者中的高检出率及ALK抑制剂PF-02341066在Ⅰ期临床试验中显示出的良好疗效使EML4-ALK成为非小细胞肺癌又一靶向治疗点.
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abstractsIndividualized treatment in non-small cell lung cancer has reached a consensus today and targeted therapy is one of the important parts of it.EML4-ALK is a new molecular subtype discovered in non-small cell lung cancer cells.The high detection rate in patients who are Asian,female,with never or light smoking history,adenocarcinoma and the good curative effect of PF-02341066,a kind of ALK inhibitor in period Ⅰ clinical trials,make EML4-ALK be another targeted therapeutic target for non-small cell lung cancer.
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