摘要3型固有淋巴样细胞(ILC3s)是固有淋巴样细胞的一个亚群，以表达维甲酸相关孤核受体γt和产生白细胞介素(IL)-17、IL-22为特征，在组织黏膜的修复、稳态、感染和炎症中发挥重要作用。ILC3s与树突状细胞、中性粒细胞密切相关，而这些细胞与IL-17、IL-22均参与了慢性阻塞性肺疾病肺组织的免疫炎症反应。本综述基于ILC3s的免疫功能，重点关注其在慢性阻塞性肺疾病中的研究进展。

abstractsGroup 3 innate lymphoid cells (ILC3s) are a subpopulation of innate lymphoid cells characterized by the expression of retinoic acid-related orphan receptor γt and the productions of interleukin (IL)-17 and IL-22.These cells are predominantly found in tissue mucosa and play a crucial role in repair, homeostasis, infection, and inflammation.ILC3s are closely related to dendritic cells and neutrophils, and involved in the immune inflammatory response in lung tissue associated with chronic obstructive pulmonary disease alongside IL-17 and IL-22.This review focused on the immune function of ILC3s, highlighting recent research progress in the context of chronic obstructive pulmonary disease.