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采用铲状电极行经尿道膀胱肿瘤整块剜除术治疗非肌层浸润性膀胱癌的临床价值

Clinical application of transurethral bladder tumor enucleation with spade electrodes in the treatment of non-muscle invasive bladder cancer

摘要目的:分析采用铲状电极行经尿道膀胱肿瘤整块剜除术治疗非肌层浸润性膀胱癌患者的临床应用价值。方法:将本院2016年1月至2019年11月收治的125例非肌层浸润性膀胱癌患者依照手术方案不同分为观察组(29例)和对照组(96例),对照组采用普通环状电极行经尿道膀胱肿瘤电切术治疗,观察组采用铲状电极行经尿道膀胱肿瘤整块剜除术治疗。记录患者的手术时间、术中出血量、术后血红蛋白水平、术后留置导尿管时间、术后一年复发率等指标;术前及术后6个月采用残余尿量(PVR)、最大尿流率(Q max)和生活质量(QOL)评分对患者的临床症状和生活质量进行评估。 结果:观察组的手术时间、术中出血量和留置导尿管时间均明显低于对照组,血红蛋白水平明显高于对照组,差异均有统计学意义( P<0.05);治疗后观察组患者的Q max明显高于对照组,PVR及QOL评分明显低于对照组,差异均有统计学意义( P<0.05);观察组的低度恶性倾向、中度恶性倾向和总复发率均明显低于对照组,差异有统计学意义( P<0.05),但两组高度恶性倾向复发率比较,差异无统计学意义( P>0.05)。 结论:采用铲状电极行经尿道膀胱肿瘤整块剜除术治疗非肌层浸润性膀胱癌,可有效提高临床疗效,改善患者的生活质量和临床症状,并能有效降低患者的术后复发率。

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abstractsObjective:To analyze the clinical value of the treatment of non-muscle invasive bladder cancer with spade electrodes for transurethral bladder tumor mass excision.Methods:From January 2016 to November 2019, 128 patients with non-muscle invasive bladder cancer admitted in our hospital were divided into observation group(29 cases) and control group(96 cases) according to different surgical protocols. The control group was treated by tranurethral resection of bladder tumor with ordinary ring electrode, and the observation group was treated by tranurethral resection of bladder tumor with spade electrode. The operation time, intraoperative blood loss, postoperative hemoglobin level, postoperative indwelling catheter days and one-year postoperative recurrence rate were recorded. Clinical symptoms and quality of life were assessed by residual urine volume (PVR), maximum urine flow rate (Q max) and quality of life (QOL) scores before surgery and 6 months after surgery. Results:The operation time, bleeding volume and days of indwelling catheter in the observation group were significantly lower than the control group, and the hemoglobin level was significantly higher than the control group, and the differences were statistically significant ( P<0.05); Q max in the observation group after treatment was significantly higher than the control group. The observation group's low-grade malignant tendency, moderate-grade malignant tendency and total recurrence rate were significantly lower than the control group, and the difference was statistically significant ( P<0.05), but there was no significant difference between the two groups of patients with high-grade malignant tendency ( P>0.05). Conclusions:Patients with non-muscle invasive bladder cancer treated with shovel electrodes for transurethral resection of bladder tumors can effectively improve clinical efficacy, improve patients'quality of life and clinical symptoms, and effectively reduce the postoperative recurrence rate.

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DOI 10.3760/cma.j.cn431460-2020200703-00002
发布时间 2026-01-27(万方平台首次上网日期,不代表论文的发表时间)
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