摘要目的:评价一次性电子输尿管软镜裸镜联合钬激光治疗10~20 mm肾结石的疗效。方法:选取本院2019年1月至2021年6月收治的80例10~20 mm肾结石患者进行前瞻性研究，将患者随机分为观察组(裸镜)和对照组(置放输尿管软镜鞘)，每组各40例。均采用一次性电子输尿管联合钬激光碎石术进行治疗。比较两组患者的术中发热、术中出血、手术时间、术后结石清除率及不良反应等情况。结果:两组患者均一次性手术成功进镜并碎石。术中无输尿管穿孔、撕脱、大出血等并发症发生。两组患者的术中出血量、术中发热、手术时间、术后4周结石清除率比较，差异均无统计学意义(均 P>0.05)；而对照组的术后出血、术后发热发生率高于观察组，差异均有统计学意义(均 P<0.05)。 结论:一次性电子输尿管软镜裸镜联合钬激光治疗10~20 mm肾结石是安全、有效的。

abstractsObjective:To evaluate the effect of holmium laser combined with naked ureteroscope in the treatment of 10-20 mm kidney stones.Methods:A prospective study was conducted in 80 patients with 10-20 mm kidney stones admitted to our hospital from January 2019 to June 2021. The patients were randomly divided into observation group (naked lens, 40 cases) and control group (soft ureteral lens sheath, 40 cases) , all of which were treated by disposable electronic ureteral combined with holmium laser lithotripsy. The intraoperative fever, intraoperative bleeding, operative time, postoperative stone clearance rate and adverse reactions were compared between the two groups.Results:All patients in both groups were successfully treated with intraoperative lithotripsy. No complications such as ureteral perforation, avulsion and massive bleeding occurred during the operation. There were no significant differences in intraoperative blood loss, intraoperative fever, operative time and stone clearance 4 weeks after surgery between the two groups (all P>0.05). The incidence of postoperative hemorrhage and fever in control group was higher than that in observation group, and the differences were statistically significant (all P<0.05). Conclusions:It is safe and effective to treat 10-20 mm kidney stones with holmium laser and naked electron ureteroscope.