换一批
换一批肿瘤相关树突状细胞、巨噬细胞和髓系抑制细胞的研究进展
Research advance in Tumor-associated dendritic cells,macrophages,and myeloid derived suppressive cells
摘要肿瘤能够通过多种机制有效逃避机体的免疫反应,这些机制不仅涉及肿瘤细胞本身,而且与宿主免疫反应功能受损有关.肿瘤相关树突状细胞(TADC)、髓系来源抑制细胞(MDSC)和肿瘤相关巨噬细胞(TAM)等在肿瘤免疫逃逸过程中能够诱导免疫抑制反应,这些研究将会为抗肿瘤免疫治疗提供可能的新策略.
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abstractsTumors may effectively evade the immune system by several mechanisms which are not only confined to cancer cells but also may be related to the impaired function of immune responses.Tumor associated dendritic cell(TADC),myeloid derived suppressive cell(MDSC)and tumor associated macrophage(TAM)have been found to play a critical role in inducing immunosuppression in tumor immune escape.These researches may provide new strategies for immunotherapy against tumors.
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关键词
肿瘤相关树突细胞髓系来源抑制细胞肿瘤相关巨噬细胞免疫逃逸肿瘤源性因子Tumor-associated dendritic cell,Myeloid derived suppressive cellTumor associated macrophage,Immune escape,Tumor derived factors
分类号
R73
栏目名称
综述
DOI
10.3760/cma.j.issn.1673-4394.2008.06.009
发布时间
2009-01-05
基金项目
国家自然科学基金
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