换一批
换一批摘要自然杀伤(NK)细胞是体内重要的免疫细胞,而其表面的活化性受体在其发挥相应生物学功能中扮演了关键的角色.其中Ly49s3是广泛表达在多种品系大鼠NK细胞上的杀伤凝集素样受体(KLR)家族的成员,由大鼠4号染色体NKC编码,可通过识别相应的MHC I类分子,向NK细胞传导活化性信号,激活NK细胞发挥相应的生物学功能.
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abstractsNK cells are important immune cells and receptors expressed on their surfaces play crucial roles in NK cells' functions. As a member of killer cell lectin-like receptor(KLR), Ly49s3 is widely expressed in a variety of strains of rats and encoded by NKC on chromosome 4. It can transduct signals to NK cells by recognizing MHC-Ⅰ molecules and activates NK cells.
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