冠状病毒疾病对人和动物眼部影响的最新研究进展
Recent advances in the effects of corona virus disease on the eyes of humans and animals
摘要2019年12月全球出现严重的急性呼吸系统综合症冠状病毒-2(acute respiratory syndrome coronavirus-2, SARS-CoV-2)引起的新型冠状病毒(CoV)疫情。一直以来,关于CoV眼部感染的报道屡见不鲜,但具体的发病机制尚未阐明。前期研究表明,在猫和鼠的动物模型中,冠状病毒会引起如结膜炎、角膜炎、前葡萄膜炎、视网膜炎和视神经炎等多种眼部感染。文章重点综述了人和动物冠状病毒引起的相关眼部感染,为进一步研究人类冠状病毒感染对眼部的影响奠定重要的基础。
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abstractsFrom December 2019, a novel coronavirus (CoV) epidemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged worldwide.There have been the reports of ocular infection caused by CoV since then. The ocular implications of human CoV infections have not been widely studied. However, CoVs have been known to cause various ocular infections in animals. Clinical entities such as conjunctivitis, keratitis, anterior uveitis, retinitis, and optic neuritis have been documented in feline and murine models. The review will summarize the animal CoVs and ocular infections, that will serve as a start for further research on the ocular implications of human CoV infections.
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