摘要背景 心脏事件的高发生率和低生还率严重威胁着人类健康.研究表明低温治疗有望改善心肺复苏(eardiopulmonary resuscitation,CPR)后患者的神经功能恢复.在临床中治疗性低温的具体实施仍存在较多的争议.目的 就成年人心搏骤停复苏后治疗性低温的具体实施进展作一综述.内容 对于初始为室颤的院外心搏骤停后自主循环恢复的成年人昏迷患者,应尽快予低温治疗,对于院外非室颤或院内心搏骤停患者亦可实施治疗性低温.目前仍无资料表明哪一种降温方法最好,诱导达到靶目标温度后,维持中心体温在32℃～34℃并至少持续12 h～24 h,缓慢复温,密切监测,防止并及时处理并发症.趋向 低温治疗是CPR后患者脑保护的一项重要措施,其应用的时机、方式、持续时间、副作用的防治等,仍需要大量循证学依据.

abstractsBackground The high incidence of heart attacks and low survival rate is a serious threat to human health.Therapeutic hypothermia is expected to improve neurological recovery of patients after cardiopulmonary resuscitation (CPR) in some studies.However,the application of therapeutic hypothermia still remains controversial in clinical treatment. Objective This review summarizes the advance in practical aspects of therapeutic hypothermia on CPR after adult cardiac arrest. Content The guideline recommended that comatose adult patients with return of spontaneous circulation after out-of-hospital VF cardiac arrest should be cooled to 32 ℃ to 34 C for 12 h to 24 h.Induced hypothermia also may be considered for comatose adult patients with spontaneous circulation after in-hospital cardiac arrest of any initial rhythm or after out-of-hospitalcardiac arrest with an initial rhythm of pulseless electricactivity or asystole.Providers should closely monitor patient core temperature after spontaneous circulation and actively intervene to avoid hyperthermia and other complications. Trend Therapeutic hypothermia is an important measure for cerebral protection in patients after CPR,however the timing of its application,method,duration and prevention and treatment of side effects still need a lot of evidence-based studys.