摘要固有淋巴细胞（innate lymphoid cells, ILCs）是新近被关注的一类固有免疫细胞，其中Ⅱ型固有淋巴细胞（type Ⅱ innate lymphoid cells, ILC2）作为其主要的细胞亚群，介导炎症、组织修复等病理生理过程。脓毒症时固有免疫系统被激活，引起过度炎性反应和免疫抑制。文章综述近年来国内外有关2型免疫反应在脓毒症发生、发展中的作用。通过阐述ILC2的来源、活化因子、细胞间的沟通与最新研究进展，揭示ILC2在脓毒症中的重要作用。

abstractsInnate lymphoid cells (ILCs) are a type of innate immune cells which have attracted increasing attention in recent years. Type Ⅱ innate lymphoid cells (ILC2), as a major cell subpopulation, are involved in mediating multiple pathophysiological processes such as inflammation and tissue repair. During sepsis, the innate immune system is activated, resulting in excessive inflammatory responses and immunosuppression. In this review, we summarize the effects of type Ⅱ immunity on the pathogenesis of sepsis based on recent research at home and abroad. By describing the source of ILC2, activating factors, communication between cells and the latest research progress, we reveal the important role of ILC2 in sepsis.